Carla Talbot is the wife of Brigadier General Glenn Talbot. They have a son named George.
In her first episode, she was walking with her husband and son through Potomac Plaza in Washington, D.C. jokingly discussing George's future. The eleven-year old told his parents that since he liked boats, naval aspirations which did not sit well with his Air Force father.
Her form is later duplicated by Agent 33 in order to gain access to General Talbot's base. When the real Carla turns up, the general is understandably suspicious, and his subsequent words and actions are something he rectified later.
In season five, Daisy helps Glenn Talbot to contact his family. Unbeknownst to Daisy, Carla was tricked into activating Talbot's Hydra brainwashing. Later on, she is attacked by Talbot after he absorbed Gravitonium .