Prior to his time in S.H.I.E.L.D., Grant was arrested and sent to prison for arson. He was approached by Victoria Hand, who convinced him that he could be a "good man". With this aim in mind, he accepted Hand's offer to join S.H.I.E.L.D. 
Life at HYDRAEdit
Ward chose to become a double agent for HYDRA and met Skye, whom he later fell in love with. He also learned that she had Inhuman DNA. Consequently, this discovery prompted him to continue fighting with the resistance. As a HYDRA agent, Ward was tasked with finding and capturing Inhumans with his fellow agent Skye. The relationship between Skye and Ward develops and Skye talks about the prospect of living together. However, Ward rejects Skye's proposition. 
Not long after, Skye is replaced by Daisy Johnson, her counterpart from the real world. As Ward is unaware of this change, he is baffled by Skye's dramatic change in personality. The pair were called into work at the HYDRA Triskelion, and attended a meeting lead by Melinda May, where he is ordered to interrogate a man named "Jason Rajan". Though due to his alliance with SHIELD, he is aware that the man's real identity is Vijay Nadeer. During the interrogation, a panicked Ward punched Nadeer to stop Daisy from finding out about his allegiance to the resistance. Shortly after, Ward confronted Daisy on her behavior, who responds by saying she needed space in their relationship. 
Still unnerved by her behavior, Ward followed Daisy and witnessed his girlfriend speaking with Jemma Simmons. He immediately approached the pair and questioned Daisy on whenever Jemma was her source in the resistance. Prior to the meeting, Daisy was aware of Jason Rajan's real name, something only members of S.H.I.E.L.D. would know. In truth, Daisy had no ties with the resistance and so refused Ward's accusations. Ward, however, revealed his allegiance to SHIELD by shooting a nearby HYDRA agent. The three flee from the scene in Simmons' car but were chased by HYDRA agents. They arrive at Daisy's apartment, where Ward is surprised to learn that the girl he knew as Skye was actually called Daisy Johnson. 
Due to his betrayal against S.H.I.E.L.D. becoming more noticeable, Ward returned to S.H.I.E.L.D. and began working within the resistance. He convinced Jeffrey Mace to allow Jemma Simmons and Daisy Johnson access into S.H.I.E.L.D. 
- Victoria Hand: Unlike his main reality counterpart, Ward had a friendly relationship with Hand. During his time in prison, Ward became distressed and miserable, believing his life was effectively over. Hand convinced him of the opposite and stressed that he could lead a better life. Ward accepted Hand's offer of recruitment into S.H.I.E.L.D. and from hereafter lead a more heroic life. During a discussion with Daisy, Ward talks fondly of Hand and how changed his life. 
- Skye: Grant developed a romantic relationship with the Framework version of Daisy. He and Skye were fellow HYDRA agents who were both tasked with hunting Inhumans on a daily basis. Prior to the real Daisy taking Skye's place in the Framework, the couple went on a vacation and Ward looked back fondly on the trip. Skye also aimed to move in with Ward, though Ward was less enthusiastic about this prospect. After learning that Framework Skye was replaced with Daisy, Ward desperately hoped that Skye would return to him after Daisy left.
- Daisy Johnson: Initially, Daisy didn't trust the Framework version of Ward, believing he was just like the original. But, after spending enough time with him and seeing how much he loved her, she started to warm up to him. Even trying to stop him from staying behind to fight the Framework version of HYDRA. After an emotional talk with Ward, Daisy finally came to understand the real Grant Ward and seemed to have finally forgiven him for everything he did, realizing there was still good left in him.
- This is the third character Brett Dalton has portrayed on the show. Brett also portrays the original Grant Ward and the Inhuman Hive.
- Framework Ward's past appears similar to the original Grant Ward. Both characters were arrested for arson and sent to prison. The original Ward was approached by John Garrett who recruited him to HYDRA. While, in the Framework, Ward was instead approached by Victoria Hand.
- With the introduction of Project Looking Glass, many fans theorized that the Framework version of Grant Ward would be transferred to a physical body in the main reality, similar to what occurred to AIDA. This theory was disputed by Jed Whedon who confirmed that Framework Ward, Trip, and Bakshi will not exist outside the Framework.