During an operation by S.H.I.E.L.D. to track and apprehend Ian Quinn, Agent Coulson's team marked Carlo Mancini's security team as protecting a product to be delivered to Quinn via train. Unknown to Coulson, Sofia and her team were tipped off to S.H.I.E.L.D.'s plan by Luca Russo, a corrupt Italian law enforcement agent who was being payed off by Cybertek to protect their interests in Italy. Sofia, posing as a standard train passenger, attempted to eliminate Agent Grant Ward. However, Ward was able to disarm and incapacitate both Sofia and her two teammates.
Later, at Quinn's villa, Sofia was present with Mancini and the rest of their team as they were awaiting their payment from Quinn. Instead, they were confronted by Mike Peterson, codenamed "Deathlok," who single-handedly killed Sofia and the rest of her team.